Protective Effect of Melatonin on Kainic Acid Induced-Liver Damage and Immune Modulatory Cytokines

Liver toxicity or otherwise toxic hepatitis occurs when liver develops inflammation because of exposure to a toxic substance. Liver is a vital organ engaged in several vital functions, including removing most drugs and chemicals from the bloodstream, and breaking them down so that they can be quickly eliminated from the body. Breaking down toxins creates byproducts that can be highly damaging to the liver. Although the liver has a great capacity for regeneration, constant exposure to toxic substances can cause serious and sometimes irreversible-harm. Excessive consumption of dangerous substances can overwhelm the liver’s purification ability and the toxins may begin to take over, creating a poisonous environment in the liver.